MRC 2 Lens Crystallisation Microplate

The  SWISSCI  MRC  Crystallisation  Plate  is   a breakthrough for protein crystallisation presented in a 96-well plate format.

The plate was developed at the MRC Laboratory of Molecular Biology  (Cambridge,  UK)   in   collaboration   with   Dr.   Jan Löwe. It is the result of many years of experience in successful robotic high-throughput crystallisation and combines many of the necessary features not earlier available to the crystallographer.

The SWISSCI MRC crystallisation  Plate  offers  unique properties that make it ideal for both nanolitre crystallisation screening and mircolitre optimisation alike. Made from optically superior polymer and with a new design of the wells, the plate allows easy crystal viewing and retrieval.

The Advantages of the MRC Crystallisation Plate

Easy crystal retrieval
Raised wide wells make the crystal mounting especially easy.

Easy viewing
The wells are a wide conical shape and have a lens effect for perfect illumination.

The micro-numbering ensures you will never get lost again (visible by microscope).

The optically superior polymer is UV transmissible and may be used to differentiate between salt and protein crystals.

Better sealing

Wide partition walls between the wells give plenty of area for good sealing with tape.
No central bending occurs in this very robust structure.
Excellent long term storage – no sample evaporation.

Wide range of volumes
Typical volumes are 50-100 μl of reservior and 50 nl-5 μl drop size. The 192 optical wells offer twice the number of experimental constructions.

ANSI/SLAS 1-2004 Standard
The plates are designed to the 96-well ANSI/SLAS 1-2004 standards for all common holders andexternal numbering (A-H, 1-12) with corner location make the plate easy to use in a robotic sampler.
The MRC plate is suitable for centrifugation.

The unique 2 drop protein crystallisation plate offers a new way of sitting-drop crystallography.
The 192 wells are optically perfect designed to observe crystals under a microscope.
The wells are doubled, providing an unique security of growing crystals.

MRC plate features

• Easy to fill 96-well structure – typically 85µl per buffer well.

• Standard ANSI/SLAS 1-2004 form for automation.

• Optically perfect wells with lens effect for a better view with  microscope.

• Microscopic identifier within wells, simplifying the orientation under the microscope.

• Maximum volume of the buffer reservoir is 100µl, typically 100 nanolitres is used for the protein well filling.

• Grown crystals are easy to identify and to remove from well due to a low-binding  polymer.

• Plate with 2 wells for each sample, better growing security with duplicates or the ability to use well two as a mixing station.

• Wells fill without micro-droplets jumping out due to static  effects.

• Wells can be individually sealed with a perfectly flat upper surface – there is a large land area designed to ensure integrity of each well section.

Order details:

• 2 Well Plate in UVP / Box of 100 / Code MRC96T-UVP

• 2 Well Plate in Polystyrene / Box of 100 / Code MRC96T-PS

MRC 2 Lens Crystallisation UVXPO Microplate

Order details:

• 2 Well Plate in UVXPO / Box of 100 / Code UVXPO-2LENS