These reagents can perturb and manipulate sample-sample and sample-solvent interactions, as well as perturb water structure which can alter and improve both the solubility and crystallization of a sample. Additives can stabilize or engender conformity by specific interaction with the macromolecules. There are numerous reports of the use of additives to improve the quality and size of macromolecular crystals.^1-5

Additive screen reagent classifications include multivalent, salt, amino acid, dissociating agent, linker, polyamine, osmolyte, chaotrope, co-factor, reducing agent, chelating agent, polymer, carbohydrate, non-detergent, amphiphile, detergent, non-volatile organic and volatile organic.

Additive Screen contains 96 unique reagents, 1 ml each.

Additive Screen HT contains 96 unique reagents, 1 ml each, in a single Deep Well block.

Additive Screen 是一个试剂库，可以影响生物大分子的溶解度和结晶，包括可溶性蛋白和膜蛋白。

这些试剂可以干扰和操纵样品-样品和样品-溶剂的相互作用，以及可以改变和改善样品溶解度和结晶的水结构。添加剂可以通过与大分子的特定相互作用来稳定或产生一致性。有许多关于使用添加剂来改善大分子晶体的质量和尺寸的报道。 1-5

添加剂筛选试剂分类包括多价、盐、氨基酸、解离剂、连接剂、多胺、渗透剂、离液剂、辅助因子、还原剂、螯合剂、聚合物、碳水化合物、非去污剂、两亲物、去污剂、非挥发性有机物和挥发性有机物。

Additive Screen 包含 96 种独特的试剂，每种试剂 1 ml。

Additive Screen HT 在单个 Deep Well 模块中包含 96 种独特的试剂，每种试剂 1 ml。